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Investment Q&A

Not investment advice or solicitation to buy/sell securities. Do your own due diligence and/or consult an advisor.

Q: Trying to decide whether to keep SIS or look for something with a greater return potential. When I look at the profile, (evening Dec 18), I see that it is trading at a P/E of 25.31 which seems to be based on earnings of .86, which is very close to mathing out at the share price shown of $22.25.
I also see that the current consensus estimate for EPS in 2026 is 1.37. If SIS trades at a similar P/E in Dec 2026, as it is now, 25.31, then that would give a potential share price of $34.67, approximately 56% above the current price. I see that target prices are $26-$30. Even at $30, that would make the P/E in Dec 2026 about 21; below where it is now. So, is SIS over valued now or are the estimates too low and this should be kept or bought? The high and low P/E shown in the data are very far apart so not really applicable.

An interesting note to add is that I asked Google AI for the P/E in the last 5 years and it shows the following for Dec of each of the years shown:
2020-27.4
2021-102.7 Covid outlier I guess
2022-25.5
2023-26.2
2024-29.1
2025-25.4

Sorry for the length here but don't know how else to explain my predicament...

Was going to make this public but didn't because of length- feel free to change the status if you wish.
Read Answer Asked by Robert on December 22, 2025
Q: NRXS Can you give me you opinion on this stock. Do you it has potential from current prices?
Read Answer Asked by Imtiaz on December 22, 2025
Q: Would you recommend starting a new position now in these big pharma stocks with rotation out of the tech sector lately? All three have decent PE, PEG and PS ratios and have been fared well in last few bear markets overall. What would your recommended allocation be across the three stocks for an investment of time line of 5 years?
Thanks!
Read Answer Asked by Scott on December 17, 2025
Q: Hi Peter and Team,

This is the first question for this Middlefield ETF. I realize that its MER is quite high, but its performance appears to be above its peers. I am also impressed with its 5.085% distribution yield and its very low Beta of 0.34.

Portfolio Analytics indicates that we’re too low in the Healthcare sector as well as US holdings. This ETF could reduce the imbalance.

What is your opinion on MHCD at this time? Are there other ETFs in this sector that you find more compelling?

Thanks as always for your valued insight.
Read Answer Asked by Jerry on December 16, 2025
Q: May I have your comments on DVAX? They seem to have strong earnings but is their outlook for 2026 negative? Please also comment on their cash flow, debt, dividend sustainability, share buyback, insider ownership and another aspects you feel are noteworthy. The stock charts red because it has declined 16% YTD. I do not own the stock. The stock seems to be too small to be a value trap but I am a little puzzled why it can’t seem to gain traction.
Thank you,
Jim
Read Answer Asked by James on December 16, 2025
Q: Greetings 5i, I would like to revisit the investment thesis for Ilumina, sold it for a tax loss but the stock spiked up on earnings and has continued to rise. Please provide an analysis of its future prospects and your opinion as to whether or not this is a buy now. Or, is there a better option in this field? I already have a good sized position in Intuitive Surgical. Thank you.
Read Answer Asked by Barbara on December 15, 2025
Q: Hi Peter and team,

Our Healthcare sector is under-represented according to Portfolio Analytics. We do own VHI and are down, but most of what I read indicates a compelling case for VHI. As an example, National Bank Direct Brokerage rates it as outperform. Its current position is 0.76% of our Total Portfolio Equity Weight, and our only other sector holding (other than some diversified ETFs) is SIA with a Total Portfolio Equity Weight of 3.34%.

Would you be a buyer at current levels?

As always, thanks for your insight.
Read Answer Asked by Jerry on December 15, 2025
Q: I'm analyzing some pharma companies for a potential single company to add to the portfolio. I know you like Cipher in Canada. I'm looking for outsized long term returns, so I'm excluding mega caps like Eli Lilly etc. More looking to get in earlier and hold a company that has the criteria to be a big name down the road. Can you compare CPH to KRYS, which is a US company that filters pretty well for what I'm looking for. Let me know which of the 2 looks like the better choice? Thx
Read Answer Asked by Adam on December 10, 2025
Q: I understand there has been some type of study which shows people who have taken the Shingles vaccine are less likely to develop Alzheimer’s like diseases. The scientific community seems not to know why this is so. There are a lot of unknowns on this study to say the least. Do you know any first rate Pharma companies that are leaders in the development and manufacturing the Shingles vaccines? I know there are a number of Shingles vaccines out in the marketplace, probably made by different companies. Does Bloomberg have anything to say on the subject? Any thoughts you have would be appreciated.
Jim
Read Answer Asked by James on December 04, 2025